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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.

NewThe following product availability updates are due on 25 June 2025.

Please check with your local pharmacy.

The following product availability updates are due on 25 June 2025

  • Please check with your local pharmacy

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A new study found that Viagra can cause more problems than it cures, the most common cause of erectile dysfunction.

But the Food and Drug Administration has long had to adapt the drugs' warnings.

It has long warned that the effects of older drugs could cause dangerous side-effects. Last month, FDA regulators found that some drugs, including antidepressants, can cause heart problems in people with low blood pressure and stroke.

But this week, a new study of the drugs' safety found that some of them could also cause blood pressure to increase.

It was the first time the agency had warned about these problems.

The drugmaker said in a statement that it would "review all of the available evidence" to make its warning aware of the dangers.

It said it was also working with a panel of experts to evaluate the drugs' risks.

The study was funded by Pfizer Inc., the maker of the anti-impotence drug Viagra.

It found that Viagra, which the FDA has approved for use in the United States, could cause blood pressure to rise to dangerously high levels.

The drugmaker said it was reviewing its safety findings.

It said it is "reviewing the available evidence" and is working with a panel of experts to evaluate the drugs' risks.

The FDA is also considering other options for treating erectile dysfunction.

It has advised that patients taking the erectile-dysfunction pill should get an "immediate medical assessment" about the drugs' risks.

There have been a handful of studies that have found that Viagra can cause serious side effects.

A 2006 study of Viagra's effects on the heart found that it also caused blood pressure to increase by more than 2 per cent. It also caused a rare condition known as "heart-related angina" or "heart attack."

Viagra, which has been approved for use in the United States, is a member of the class of drugs known as phosphodiesterase type 5 inhibitors.

The agency said the results could lead to new drug applications for the drug. It also recommended that Pfizer consider other options to treat erectile dysfunction, including medications that can increase blood flow to the penis or improve blood circulation.

The FDA has not yet issued a ruling on Viagra's effectiveness.

Still, it is a good idea to read about the risks of older drugs that have been shown to cause problems.

© 2013 The Associated Press. All rights reserved.

The Associated Press

Published by Time magazine.

AP

© 2013 AP

Originally Published 2013 by AP, an imprint of The Avedis, is owned by The Australian Government Publishing, Inc.

Copyright 2013 Time

Copyright 2013 AP

Originally published 2013 by AP, an imprint of The Avedis, is owned by The Australian Government Publishing, Inc.

Originally:

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How to take Viagra Connect

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